In recent years, hormone-dependent dermatitts (HDD) has become a common disease in dermatology due to the extensive and non-standard application of topical glucocorticoid preparations. With characteristics such as multiple morphological damage, glucocorticoid dependence and high recurrence, the disease seriously affects the patient's appearance and physical and mental health, and has become a difficult problem in clinical. From May to November in 2013, we used medical skin care cosmetic Skin Barrier Repairing Gel in the treatment of hormone-dependent dermatitis for 30 cases,achieving good results as follows.
Hormone-dependent dermatitis diagnosis and treatment guidelines drafted by the professional group of Chinese Medical Association of Dermatology Branch considered that improper use of glucocorticoids, improper indications and selection and administration site, long external use or taking glucocorticoids as cosmetics were the main inducing factors for HDD. The main symptoms were epidermis and dermis thinning,epidermal barrier damage and telangiectasia. In recent years,Qi and others studied the changes of TEWL, histopathologies and lamellar body density observed by electron microscopy by comparing the HDD patients with normal human. Results showed that skin barrier structure of HDD patients was damaged compared with normal skin. It is of great significance to restore the skin barrier for the treatment of hormonedependent dermatitis.
Skin Barrier Repairing Gel can repair and maintain the skin barrier function from the aspects of epidermis and sebum lm. Skin Barrier Repairing Gel was employed in this study to treat hormone-dependent dermatitis for 4 weeks. The skin barrier function was significantly improved (P <0.05), and the clinical effective rate was 86.66%. The result was better than that in control group (P <0.01), which is an ideal choice for the treatment of hormone-dependent dermatitis. What's more,the product does not contain allergens preservatives, hormones,heavy metals, hydroquinone, alcohol, pigments, flavors and other harmful ingredients. It takes effects in a moderate and comfortable way with no stimulation, which is more easily accepted by patients.
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