How Many Sessions of ZQ-II PLLA Nutrients Fills Are Needed for Melasma Patients?

April 30, 2025
By ZQ-II®


A Comprehensive Approach to Treating Melasma with ZQ-II PLLA Nutrients Fills

Melasma, often referred to as "butterfly spots" or "pregnancy mask," is a persistent skin condition characterized by brown or grayish pigmentation. The patches typically appear on the cheeks, forehead, nose, and upper lip, and it’s known for being notoriously difficult to treat. Despite various therapies available, melasma remains a challenging issue due to its unclear pathogenesis and tendency to recur.

For patients with melasma, one of the more effective treatments to improve skin texture and tone is ZQ-II PLLA Nutrients Fills. This mesotherapy solution delivers a combination of poly-L-lactic acid (PLLA), tranexamic acid, and nonapeptide-1 to help restore skin hydration, improve skin tone, and stimulate collagen production. However, before pursuing this treatment, it’s important to understand how many sessions are typically required and which patients are suitable for this approach.

When Is ZQ-II PLLA Nutrients Fills Suitable for Melasma Patients?

Melasma can manifest in various forms, and it’s crucial to identify the stage of melasma before choosing an appropriate treatment. ZQ-II PLLA Nutrients Fills is most effective for stable-stage melasma (mild to moderate cases) and should not be used in patients with more active or inflammatory melasma.

1.Inflammatory Melasma: Patients with inflammatory melasma, characterized by noticeable inflammation and severe damage to the skin’s basement membrane (detectable through dermatological imaging), are not suitable candidates for ZQ-II PLLA Nutrients Fills. These patients should prioritize anti-inflammatory or reparative treatments to stabilize the condition before considering mesotherapy.

2.Active-Stage Melasma: Patients with active melasma—characterized by active melanocytes, recent pigment spread, and symptoms like erythema (redness), dryness, or itching—should avoid ZQ-II PLLA Nutrients Fills. For active melasma, it is advisable to allow the condition to stabilize before undergoing treatments like PLLA mesotherapy.

3.Stable-Stage Melasma: For patients whose melasma has stabilized and is in a mild-to-moderate phase, ZQ-II PLLA Nutrients Fills can be an effective treatment to improve skin appearance. This treatment not only helps with hydration but also stimulates collagen production, which can help improve the skin’s overall texture and tone.

How Many Sessions of ZQ-II PLLA Nutrients Fills Are Needed?

The treatment course for melasma with ZQ-II PLLA Nutrients Fills generally involves 3 sessions per course, spaced 20-30 days apart. Based on feedback from clinical cases, patients in the stable stage with mild to moderate melasma typically begin to see significant improvements after 1-2 full treatment courses (3 sessions each), with visible reductions of at least 20%-30% in pigmentation.

However, because melasma is highly individualized, the number of sessions required may vary from patient to patient. Some patients may see results after just one treatment course, while others may need more sessions for optimal outcomes.

Combining ZQ-II PLLA Nutrients Fills with Other Treatments

In some cases, combination therapy may be recommended to achieve better results, particularly for patients with melasma that is resistant to standalone treatments.

1.Oral Tranexamic Acid: Tranexamic acid is known to reduce the production of melanin in the skin. Oral tranexamic acid tablets can be used alongside ZQ-II PLLA Nutrients Fills to enhance the treatment’s efficacy, especially in cases where pigmentation is deeper or more persistent.

2.Phototherapy: Photorejuvenation, picosecond lasers, or ultra-picosecond lasers can be combined with ZQ-II PLLA Nutrients Fills to target melanin in the skin and break up pigmentation. This type of phototherapy can help enhance the effects of PLLA mesotherapy, accelerating the reduction of dark spots and improving overall skin clarity.

3.ZQ-II Repair Products: Topical application of ZQ-II’s repairing series, which includes nourishing and brightening products, can complement the mesotherapy treatment by helping to maintain hydration, reduce inflammation, and speed up skin regeneration. These products are ideal for maintaining the skin’s improved texture and tone after treatment.

Expected Results

After completing a full course of ZQ-II PLLA Nutrients Fills for melasma, patients can expect the following improvements:

1.Reduction in Pigmentation: The most noticeable effect will be a reduction in the intensity and spread of pigmentation. Stable-stage melasma will show a reduction of 20%-30% in pigmentation after 1-2 courses.

2.Improved Skin Tone and Texture: The overall texture of the skin will become smoother, and the skin tone will be more even. This is due to the hydration, collagen stimulation, and brightening effects of the treatment.

3.Improved Skin Elasticity: The skin will also feel firmer and more resilient due to the increase in collagen production, leading to a more youthful appearance.

ZQ-II PLLA Nutrients Fills is an effective and safe treatment for stable-stage melasma, offering noticeable improvements in pigmentation, texture, and skin tone. For patients with mild to moderate melasma, the treatment generally requires 1-2 treatment courses (3 sessions each) to achieve a 20%-30% reduction in pigmentation. For enhanced results, combination therapies such as oral tranexamic acid, phototherapy, and the use of ZQ-II repair products may be recommended.

As with any aesthetic treatment, it's essential to consult with a qualified professional to determine the most appropriate treatment plan based on the severity of your melasma and individual skin needs. Proper care and patience throughout the process will ensure the best results.



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